Table 3 Adjusted cox regression hazard ratios for melanoma-specific survival of each stage of the 7^th and 8^th edition TNM melanoma staging system

Stage

 IA

0.03

(0.02–0.05)

 < 0.001

0.04

(0.02–0.06)

 < 0.001

 IB

0.12

(0.08–0.18)

 < 0.001

0.17

(0.11–0.26)

 < 0.001

 IIA

0.35

(0.24–0.51)

 < 0.001

0.33

(0.22–0.48)

 < 0.001

 IIB

0.66

(0.47–0.93)

0.019

0.66

(0.46–0.93)

0.017

 IIC

Reference

-

-

Reference

-

-

 IIIA

0.56

(0.35–0.91)

0.020

0.28

(0.14–0.56)

 < 0.001

 IIIB

0.94

(0.65–1.35)

NS

0.86

(0.54–1.36)

NS

 IIIC

1.95

(1.35–2.82)

 < 0.001

1.42

(1.02–1.97)

0.040

 IIID

-

-

-

4.14

(2.26–7.58)

 < 0.001

 IV

6.48

(4.04–10.37)

 < 0.001

6.57

(4.08–10.57)

 < 0.001