Fig. 4
From: Kayadiol exerted anticancer effects through p53-mediated ferroptosis in NKTCL cells
The regulatory role of p53 on kayadiol-induced ferroptosis in NKTCL cells, A Silencing of p53 by siRNAs decreased the expression of p53 at mRNA levels in YT cells. B Silencing of p53 by siRNAs decreased the protein expression of p53 in YT cells. C Expression levels of p53 and SLC7A11 were presented as means ± SD from 3 independent experiments, *P < 0.05 vi siCtl group. D Western blotting showed the effect of p53 knockout by CRISPR-Cas9 plasmid on kayadiol-induced ferroptosis in YT cells. E Quantification of the western blot signals was presented as means ± SD from 3 independent experiments, *P < 0.05