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Table 2 Prognostic analysis of characteristics and lymphocyte subsets in patients with PCa

From: A nomogram based on peripheral lymphocyte for predicting 8-year survival in patients with prostate cancer: a single-center study using LASSO-cox regression

Variables

Univariate analysis

Multivariate analysis

Hazard Ratio

95% Cl

P

Hazard Ratio

95% Cl

P

Age, years

1.10

1.04 to 1.17

< 0.001

1.10

1.03 to 1.16

0.003

T stage

      

 T0-T1

Reference

     

 T2-T4

2.45

0.94 to 6.33

0.065

1.75

0.91 to 6.43

0.078

N stage

      

 N0, Nx

Reference

     

 N1

0.95

0.46 to 1.96

0.881

   

M stage

      

 M0, Mx

Reference

     

 M1

2.07

1.10 to 3.89

0.024

   

Total CD3(+) T lymphocytes, cells/µL

      

 < 1203.05

Reference

     

 ≥ 1203.05

0.45

0.20 to 1.01

0.053

   

CD3(+) CD4(+) T lymphocytes, cells/µL

      

 < 365.1

Reference

  

Reference

  

 ≥ 365.1

0.36

0.18 to 0.74

0.006

0.30

0.14 to 0.65

0.002

CD4(+)/CD8(+) ratio

      

 < 1.10

Reference

  

Reference

  

 ≥ 1.10

0.39

0.20 to 0.74

0.004

0.47

0.24 to 0.93

0.030

Total CD19(+) B lymphocytes, cells/µL

      

 < 45.83

Reference

     

 ≥ 45.83

0.35

0.18 to 0.68

0.002

   

CD19(+) CD5(+) B lymphocytes, cells/µL

      

 < 5.76

Reference

     

 ≥ 5.76

0.33

0.15 to 0.68

0.003

   

CD3(-)CD16(+)CD56(+) NK cells, cells/µL

      

 < 238.87

Reference

  

Reference

  

 ≥ 238.87

1.73

0.91 to 3.30

0.095

2.29

1.14 to 4.62

0.020