Fig. 1

The case screening flowchart and the schematic representation of the study design. A This figure showed how the data were gathered from the “Weinichangzai” database of the First Affiliated Hospital of CMU, and all variables included demographic information, treatment information, clinical information, and laboratory indicators. There were 26 feature variables collected, and 6 key variables related to IM C_min were screened using the LASSO regression and binary logistic regression. Moreover, the study used the 6 key variables to establish a classification model. B The flowchart of study design. Abbreviations: GIST, gastrointestinal stromal tumor; CMU, Chongqing Medical University; IM, imatinib; C_min, plasma trough concentration; LASSO, least absolute shrinkage and selection operator.