Fig. 1

Overview of the somatic alteration profile in Chinese ampullary carcinoma patients. (A) Oncoprint figure: genomic alterations from 145 Chinese AMPAC patients are depicted. For each sample, mutation profile is shown in a column including 20 the most frequently altered genes. Genomic alterations included amplification, frameshift-insertion/deletion, non-frameshift-insertion/deletion, splice site, stopgain and nonsynonymous mutations. (B) The co-occurence or mutually exclusive relationship between altered genes in Chinese ampullary carcinoma patients. (C) The genomic disparities between intestinal-type and pancreatobiliary-type tumors in our cohort. p < 0.05; * p < 0.01