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Fig. 4 | BMC Cancer

Fig. 4

From: 5-Methoxytryptophan enhances the sensitivity of sorafenib on the inhibition of proliferation and metastasis for lung cancer cells

Fig. 4

Enhanced inhibitory effect of sorafenib by 5-MTP on cell migration and invasion measured by wound-healing and transwell assay. (A) Representative bright-field images show that 5-MTP enhanced the reduction effect of sorafenib on migration compared to single compound treatment in wound-healing assay. (B) 5-MTP enhanced the reduction effect of sorafenib on the number of migration cells. (C and E) Representative bright-field images showed the effect of 5-MTP and sorafenib on cell migration and invasion in a transwell assay. (D and F) Statistic results showed that 5-MTP enhanced the inhibitory effect on cell migration and invasion. Asterisks indicate a significant difference in drug-treated cells at indicated concentrations singly compared to DMSO-treated cells. *P < 0.05

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BMC Cancer

ISSN: 1471-2407

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