Fig. 5From: 5-Methoxytryptophan enhances the sensitivity of sorafenib on the inhibition of proliferation and metastasis for lung cancer cellsThe effect of combination treatment of 5-TMP and sorafenib on the expression of EMT markers by mediating the expression of phosphorylated STAT3 and Akt. (A) Combination treatment of 5-MTP and sorafenib reduced the expression of vimentin and MMP9 and increased the E-cadherin level. (B) The level of phosphorylated STAT3 and Akt showed in western blotting. Asterisks indicate significant difference in drug-treated cells at indicated concentrations singly in comparison with DMSO-treated cells. *P < 0.05Back to article page