Prediction model based on MRI morphological features for distinguishing benign and malignant thyroid nodules

BMC Cancer

Table 4 Comparison of diagnostic performance of MRI-based prediction model and five ultrasonography-based risk stratification systems

Model (Cutoff score)	Sensitivity	Specificity	Accuracy	PPV	NPV	AUC	P*	NRI	P^#
MRI-based prediction model	96.0	93.4	94.4	89.9	97.5	0.947
ACR-TIRADS (≥ category 4)	96.8	56.9	72.1	57.9	96.6	0.768	<0.001	22.36	<0.001
ACR-TIRADS (≥ category 5)	64.6	94.7	83.3	88.2	81.4	0.797	<0.001	11.11	<0.001
K-TIRADS (≥ category 4)	95.3	58.4	72.4	58.4	95.3	0.769	<0.001	21.95	<0.001
K-TIRADS (≥ category 5)	79.1	91.6	86.8	85.2	87.7	0.853	<0.001	7.54	<0.001
EU-TIRADS (≥ category 4)	95.3	58.4	72.4	58.4	95.3	0.769	<0.001	21.95	<0.001
EU-TIRADS (≥ category 5)	81.9	88.1	85.7	80.8	88.8	0.850	<0.001	8.64	<0.001
Kwak-TIRADS (≥ category 4b)	95.3	59.5	73.1	59.1	95.4	0.774	<0.001	21.26	<0.001
Kwak-TIRADS (≥ category 4c)	79.8	91.2	86.8	84.7	88.0	0.855	<0.001	7.54	<0.001
C-TIRADS (≥ category 4b)	82.3	89.4	86.7	82.6	89.2	0.858	<0.001	7.68	<0.001
C-TIRADS (≥ category 4c)	51.3	97.3	79.9	92.2	76.5	0.743	<0.001	14.54	<0.001

Data are presented as percentages with the exception of the results for AUC. Abbreviation: PPV positive predictive value; NPV negative predictive value; AUC area under the curve; NRI Net reclassification index; TIRADS Thyroid Imaging Reporting and Data System; ACR American College of Radiology; *P values were assessed using Delong tests; ^#the P value for NRI
*P values were assessed using Delong tests; ^#the P value for NRI

ISSN: 1471-2407