Fig. 3

The 50 most frequent combinations of postoperative risk factors. The 50 most frequent combinations of risk factors were probed with variables derived from the postoperative version. Risk factors and their respective frequencies are shown in the lower left corner of the figure, and the dots connected by lines represent the corresponding combinations of these variables. The bar plot illustrates the frequencies of different combinations of risk factors in the postoperative recurrence (light pink and red bars) and control (bright blue and dark blue bars) groups. The light pink bars stand for the expected frequencies of postoperative recurrence calculated according to 6-month PFS rate (15.32%, 367/2396), whereas the height of the red bar indicates the numbers of the PR group in which the actual frequency was greater than the expected frequency. The red asterisks indicate combinations in the top 10% of effect sizes, whereas a blue asterisk means combinations in the top 10-30% of effect sizes with the remaining significant but not ranked in the top 30% indicated by black asterisks