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Table 4 Multivariate analyses of PFS and OS with the Cox proportional hazards model

From: Alpha-fetoprotein predicts the treatment efficacy of immune checkpoint inhibitors for gastric cancer patients

 

Variables

Total No.

 

PFS

  

OS

 

HR

95%CI

P

HR

95%CI

P

Group

        
 

Low AFP

138

Reference

  

Reference

  
 

High AFP

20

2.891

1.648–5.070

0.000

2.198

1.207–4.003

0.010

TNM stage

        
 

III

55

Reference

  

Reference

  
 

IV

103

1.888

1.197–2.978

0.006

2.124

1.264–3.567

0.004

Treatment lines

        
 

1–2

138

Reference

  

Reference

  
 

≥ 3

20

2.743

1.657–4.541

0.000

1.575

0.892–2.781

0.118

  1. PFS: progression-free survival; OS: overall survival; AFP: alpha-fetoprotein