Fig. 3
From: Surrogacy of one-year survival for overall survival in advanced hepatocellular carcinoma
Performance of different surrogate endpoints for overall survival (OS). The size of the circle represents sample size. The correlations were weak between median progression-free survival (PFS) and median OS (A), and between PFS hazard ratio (HR) and OS HR (B). One-year (1-yr) milestone survival strongly correlated with OS: 1-yr survival rate—median OS (C) and 1-yr survival ratio—OS HR (D). There was a weak correlation between objective response rate evaluated by RECIST v1.1 (ORR) ratio and OS HR (E), while the correlation was stronger between ORR evaluated by mRECIST (mORR) ratio and OS HR (F)