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Table 1 Baseline and clinical characteristics of patients and their correlation with Endostar

From: Endostar acts as a pneumonitis protectant in patients with locally advanced non-small cell lung cancer receiving concurrent chemoradiotherapy

Characteristics

CCRT group

CCRT+Endostar group

P Value

Age(mean±sd)

59.08±10.062

62.15±8.602

0.357

Gender

  

0.911

Male

65(62.5)

39(37.5)

 

Female

11(61.1)

7(38.9)

 

Smoking

  

0.928

Non-smoker

16(61.5)

10(38.5)

 

Smoker

60(62.5)

36(37.5)

 

Pathology

  

0.844

Squamous

59(62.8)

35(37.2)

 

Adenocarcinoma

17(60.7)

11(39.3)

 

Stage

  

0.711

IIIA

34(64.2)

19(35.8)

 

IIIB

42(60.9)

27(39.1)

 

Amifostine

  

0.304

No

53(59.6)

36(40.4)

 

Yes

23(69.7)

10(30.3)

 

GTV(cm3)

  

0.062

<503.5(median)

43(70.5)

18(29.5)

 

≥503.5(median)

33(54.1)

28(45.9)

 

Total lung MLD(cGy)

  

0.161

<1450.7(median)

38(69.1)

17(30.9)

 

≥1450.7(median)

38(56.7)

29(43.3)

 

V20Gy (%)

  

0.036*

<25%

33(53.2)

29(46.8)

 

≥25%

43(71.7)

17(28.3)

 
  1. RP radiation-induced pneumonitis, CCRT concurrent chemoradiotherapy, GTV, gross tumor volume, MLD mean lung dose
  2. * P<0.05