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Table 3 The result of cost ($US) simulation of genetic screening tests for the genetic strategies

From: A cost-benefit analysis of genetic screening test for breast cancer in Iran

Cost items

Costs for population-based screening strategy

% of total cost

Costs for FH-based screening strategy

% of total cost

Genetic counseling and genetic screening BRCA tests

350,420,813

96.36

7,202,469

40.64

Preventive surgical interventions and associated costs

4,280,310

1.18

1,715,237

9.68

Preventive interventions (mammography and annual MRI)

68,157

0.02

27,312

0.15

Total direct medical costs

354,769,280

97.56

8,945,018

50.47

Total direct non-medical costs

8,881,488

2.44

8,777,327

49.53

Total direct medical and non-medical costs

363,650,768

100

17,722,345

100

Number of people entered into the models

2,176,919

2,176,919

Number of high-risk individuals identified

12,271

4,917

Cost per screening

167.05

8.14

  1. *US $1 in 2021 = 230,000 IRR