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Fig. 5 | BMC Cancer

Fig. 5

From: The novel circRNA circ_0045881 inhibits cell proliferation and invasion by targeting mir-214-3p in triple-negative breast cancer

Fig. 5

The interaction between has_circ_0045881 and miR-214-3p in TNBC cells. (A) Diagram showing the binding site between hsa_circ_0045881 and miR-214-3p. (B) The firefly and Renilla luciferase assays showed that the binding of has_circ_0045881 and miR-214-3p was controlled by MT and NC in MDA-MB-231 cells. MT, has_circ_0045881 mutation. NC, samples treated without miR-214-3p. (C) The RIP results showed that the immunoprecipitation of miR-214-3p by has_circ_0045881 (sense) was controlled by has_circ_0045881 (antisense) in MDA-MB-231 cells. miR-1178-3p was used as a negative control. The data are presented as the means ± SDs; n ≥ 3, **P < 0.01

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BMC Cancer

ISSN: 1471-2407

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