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Table 1 Summary of patients’ demographic and pathological characteristics

From: The impact of squamous cell transformation on the prognosis of patients treated with radical nephroureterectomy

Variable

 

1. UC (n=294)

2. UC-SqD (n=24)

3. SCC (n=9)

total (n=327)

P-value

P-value (1,2)

P-value (1,3)

P-value (2,3)

  

median

IQR

median

IQR

median

IQR

median

IQR

Age

 

67.20

57.4, 74.6

65.40

57.5, 75.4

71.30

67.1, 76.7

67.20

57.4, 74.8

0.595c

0.947d

0.306d

0.431d

BMI

 

23.70

21.5, 25.9

22.30

20.6, 24.3

22.20

21.0, 23.1

23.60

21.5, 25.7

0.039c

0.094d

0.046d

0.479d

Tumor volume

 

2.60

0.8, 11.7

13.60

3.3, 45.6

250.80

163.8, 299.5

3.50

1.0, 15.6

<0.0001c

0.001d

<0.0001d

0.001d

  

Count

Column N %

Count

Column N %

Count

Column N %

Count

Column N %

    

Gender

male

129

(43.9 %)

12

(50.0 %)

5

(55.6 %)

146

(44.6 %)

0.668b

0.562a

0.515b

1.000b

 

female

165

(56.1 %)

12

(50.0 %)

4

(44.4 %)

181

(55.4 %)

    

Gross hematuria

no

89

(30.3 %)

15

(62.5 %)

8

(88.9 %)

112

(34.3 %)

<0.0001a

0.001a

0.001b

0.217b

 

yes

205

(69.7 %)

9

(37.5 %)

1

(11.1 %)

215

(65.7 %)

    

Flank pain

no

226

(76.9 %)

13

(54.2 %)

2

(22.2 %)

241

(73.7 %)

<0.0001a

0.013a

0.001b

0.134b

 

yes

68

(23.1 %)

11

(45.8 %)

7

(77.8 %)

86

(26.3 %)

    

Smoking history

no

220

(74.8 %)

18

(75.0 %)

6

(66.7 %)

244

(74.6 %)

0.857a

0.985a

0.698b

0.677b

 

yes

74

(25.2 %)

6

(25.0 %)

3

(33.3 %)

83

(25.4 %)

    

Uremia

no

255

(86.7 %)

22

(91.7 %)

8

(88.9 %)

285

(87.2 %)

0.903b

0.752b

1.000b

1.000b

 

yes

39

(13.3 %)

2

(8.3 %)

1

(11.1 %)

42

(12.8 %)

    

Pathological T

≦T2

145

(49.3 %)

3

(12.5 %)

0

(0.0 %)

148

(45.3 %)

<0.0001b

0.001a

0.004b

0.545b

>T2

149

(50.7 %)

21

(87.5 %)

9

(100.0 %)

179

(54.7 %)

    

Pathological N

N0 or Nx

270

(91.8 %)

20

(83.3 %)

7

(77.8 %)

297

(90.8 %)

0.107b

0.248b

0.175b

1.000b

N+

24

(8.2 %)

4

(16.7 %)

2

(22.2 %)

30

(9.2 %)

    

LVI

no

242

(82.3 %)

15

(62.5 %)

7

(77.8 %)

264

(80.7 %)

0.051b

0.028b

0.664b

0.681b

 

yes

52

(17.7 %)

9

(37.5 %)

2

(22.2 %)

63

(19.3 %)

    

Surgical margin

no

283

(96.3 %)

21

(87.5 %)

7

(77.8 %)

311

(95.1 %)

0.015b

0.079b

0.052b

0.597b

 

yes

11

(3.7 %)

3

(12.5 %)

2

(22.2 %)

16

(4.9 %)

    

Adjuvant chemotherapy

no

227

(77.2 %)

8

(33.3 %)

4

(44.4 %)

239

(73.1 %)

<0.0001a

<0.0001a

0.038b

0.690b

yes

67

(22.8 %)

16

(66.7 %)

5

(55.6 %)

88

(26.9 %)

    
  1. a Pearson chi-square
  2. b Fisher's exact test
  3. c Kruskal-Wallis H test
  4. d Mann-Whitney U test
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BMC Cancer

ISSN: 1471-2407

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