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Table 2 Nodular characteristic of CT in validation cohort 2 BPN benign pulmonary nodule, MPN malignant pulmonary nodule, P X 2 test

From: Humoral immune response to tumor-associated antigen Ubiquilin 1 (UBQLN1) and its tumor-promoting potential in lung cancer

Nodular Characteristic of CT

MPN (%)

(n=105)

BPN (%)

(n=105)

P

Number

  

<0.001*

1

87(82.9)

60(57.1)

 

>1

18(17.1)

45(42.9)

 

Diameter(mm)

 Mean±SD

28.58±19.90

20.00±16.14

0.002*

 Range

5.3-130.9

2.0-76.5

 

 Edge sign

  

0.072

 Yes

26(24.8)

38(36.2)

 

 No

79(75.2)

67(63.8)

 

 Empty sign

  

0.023*

 Yes

8(7.6)

19(18.1)

 

 No

97(92.4)

86(81.9)

 

 Spicule sign

  

0.004*

 Yes

30(28.6)

13(12.4)

 

 No

75(71.4)

92(87.6)

 

 Vascular notch sign

  

<0.001*

 Yes

80(76.2)

48(45.7)

 

 No

25(23.8)

57(54.3)

 

 Lobulation sign

  

<0.001*

 Yes

55(52.4)

13(12.4)

 

 No

50(47.6)

92(87.6)

 

 Spines

  

0.009*

 Yes

18(17.6)

6(5.7)

 

 No

87(82.9)

99(94.3)

 

 Pleural indentation

  

0.004*

 Yes

35(33.3)

17(16.2)

 

 No

70(66.7)

88(83.8)

 

 Mediastinal lymph node enlargement

  

0.003*

 Yes

36(34.3)

17(16.2)

 

 No

69(65.7)

88(83.8)

 

 Emphysema

  

0.408

 Yes

21(20.0)

26(24.8)

 

 No

84(80.0)

79(75.2)

 

 Calcification

  

<0.001*

 Yes

3(2.9)

25(23.8)

 

 No

102(97.1)

80(76.2)

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