Fig. 10From: AMPKα2 promotes tumor immune escape by inducing CD8+ T-cell exhaustion and CD4+ Treg cell formation in liver hepatocellular carcinomaFunctional role of PRKAA2 in liver hepatocellular carcinoma. A PRKAA2 expression was depleted with shRNAs in HepG2 cells. B-E PRKAA2 knockdown significantly suppressed the proliferation (B), colony formation (C), scratch healing (D), and migration and invasion (E) of HepG2 cells. (Student’s t-test; *P < 0.05; **P < 0.01; ***P < 0.001)Back to article page