Table 2 Subgroup analysis on biochemical recurrence

Treatment pattern

RP

Radiotherapy

1.80

0.98

1.34–2.42

0.66–1.45

p = 0.052; I² = 51.9%

p = 0.444; I² = 0.0%

Sample sizes

≥ 1000

< 1000

1.51

1.66

1.19–1.91

1.09–2.51

p = 0.653; I² = 0.0%

p = 0.005; I² = 67.8%

Risk of patients

High-risk

Others

2.75

1.44

1.57–4.82

1.08–1.92

p = 0.696; I² = 0.0%

p = 0.030; I² = 56.9%

Region

Asia

No-Asia

2.05

1.31

1.27–3.31

1.01–1.71

p = 0.029; I² = 62.8%

p = 0.235; I² = 29.5%

Follow-up duration

> 2 years

≤ 2 years

1.44

2.27

1.06–1.97

1.52–3.38

p = 0.028; I² = 57.6%

p = 0.787; I² = 0.0%

Adjusted pretreatment PSA

Yes

No

1.41

2.39

1.06–1.89

1.59–3.59

p = 0.049; I² = 52.5%

p = 0.469; I² = 0.0%