Table 1 Analyses of IgG4 expression and clinicopathological features in TSCC
Variables | IgG4 expression | |||
|---|---|---|---|---|
High | Low | |||
(n = 25) | (n = 25) | P value | ||
Age | ≤ 67 | 13 | 11 | 0.571 |
> 67 | 12 | 14 | ||
Sex | male | 15 | 14 | 0.774 |
female | 10 | 11 | ||
Pathological T stage | T1/2 | 18 | 15 | 0.37 |
T3/4a | 7 | 10 | ||
Metastasis of cervical lymph node | Absent | 17 | 16 | 0.765 |
Present | 8 | 9 | ||
TNM stage | I-II | 14 | 11 | 0.396 |
III-IV | 11 | 14 | ||
Tumor size (mm) | ≤ 25 mm | 15 | 11 | 0.258 |
> 25 mm | 10 | 14 | ||
Depth of Invasion (mm) | ≤ 8 mm | 13 | 12 | 0.777 |
> 8 mm | 12 | 13 | ||
Histological differentiation | Well | 19 | 13 | 0.077 |
Mod/Poor | 6 | 12 | ||
Mode of invasion (YK classification) | 1–3 | 21 | 14 | 0.031 |
4 C/4D | 4 | 11 | ||
Visual type of proliferation | Endophytic | 17 | 16 | 0.765 |
Superficial/Exophytic | 8 | 9 | ||
Venous invasion | Positive | 10 | 11 | 0.774 |
Negative | 15 | 14 | ||
Perineural invasion | Positive | 9 | 13 | 0.254 |
Negative | 16 | 12 | ||
Lymph duct invasion | Positive | 6 | 4 | 0.48 |
Negative | 19 | 21 | ||
Foxp3 expression | High | 13 | 12 | 0.777 |
Low | 12 | 13 | ||