Table 5 Hazard ratios for 5-year DFS between different groups in the three cohorts

High risk

Vs.

Low risk

3.49

3.458–10.04

(< 0.0001)

1.372

0.7825–2.575

(= 0.2505)

2.411

2.109–4.670

(< 0.0001)

G2/High risk

Vs.

G2/Low risk

4.09

4.019–19.01

(< 0.0001)

1.733

0.8401–4.285

(0.1247)

2.881

2.409–7.410

(< 0.0001)

G2/Low risk Vs. G1

1.326

0.6317–2.686

(= 0.4751)

0.7291

0.3203–1.571

(= 0.3983)

1.004

0.5890–1.710

(= 0.9895)

G2/High risk Vs. G3

2.933

2.237–9.042

(< 0.0001)

1.153

0.5642–2.386

(= 0.6871)

1.964

1.378–3.723

(= 0.0014)