Table 2 Univariate and multivariate Cox regression analyses of overall survival

Univariate

 Age:≥ 60 yrs vs< 60 yrs

1.94(0.87–4.30)

0.105

 Gender: male vs female

1.37(0.49–3.83)

0.547

 Etiology: HBV vs others

2.30(0.84–6.28)

0.104

 AFP:≥ 100 ng/mL vs < 100 ng/mL

2.71(1.20–6.10)

0.016

 BCLC stage: B/C vs 0/A

3.95(1.71–9.10)

0.001

 ES grade: poor vs well/moderate

1.76(0.78–4.01)

0.177

 Underlying cirrhosis: yes vs no

2.15(0.90–5.17)

0.087

 CD 66b expression: present vs absent

0.61(0.28–1.36)

0.227

 NLR:≥ 2.5 vs< 2.5

1.67(0.75–3.71)

0.206

Multivariate

 Age:≥ 60 vs< 60

 Gender: male vs female

 Etiology: HBV vs others

 AFP:≥ 100 ng/mL vs< 100 ng/mL

2.74(1.17–6.44)

0.021

 BCLC stage: B/C vs 0/A

3.98(1.68–9.43)

0.020

 ES grade: poor vs well/moderate

 Underlying cirrhosis: no vs yes

 CD 66b expression: present vs absent

 NLR:≥ 2.5 vs< 2.5