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Fig. 3 | BMC Cancer

Fig. 3

From: High expression of RTEL1 predicates worse progression in gliomas and promotes tumorigenesis through JNK/ELK1 cascade

Fig. 3

RTEL1 knockdown promotes cell cycle arrest and apoptosis of glioma. (A) Flow cytometry was used to analyze the effect of transient transfection of indicated siRNAs on cell cycle distributions. RTEL1 knockdown caused G2/M phase arrested in U87 and SF295 cells. (B) The apoptosis of the indicated cells transiently transfected with siRNAs was measured by flow cytometry using the Annexin V-FITC/PI Apoptosis Detection Kit. RTEL1 knockdown promoted cell apoptosis in U87 and SF295 cells. si-N.C represents siRNA of non-target as controls; si-RTEL1-1724 represents siRNA of RTEL1; Mann–Whitney U test was used and data were expressed as mean ± SD. * p < 0.01

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BMC Cancer

ISSN: 1471-2407

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