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Fig. 7 | BMC Cancer

Fig. 7

From: High expression of RTEL1 predicates worse progression in gliomas and promotes tumorigenesis through JNK/ELK1 cascade

Fig. 7

RTEL1 knockdown inhibits tumor growth in nude mice. Dissected tumors in vivo (A), growth curves (B), tumor volume (C) and mean tumor weight (D) of the indicated groups. Mann–Whitney U test was used and data were expressed as mean ± SD. * p < 0.05, p ** <0.01. (E) Representative Ki-67 staining of xenograft tumors from the indicated groups by immunohistochemistry staining images. (F) RTEL1 knockdown inhibits the proteins level of p-JNK signaling and p-ELK1 in vivo, detected by immunohistochemistry (IHC) staining images. si-N.C represents siRNA of non-target as controls; si-RTEL1 represents siRNA of RTEL1; Scale bar, 200 μm

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BMC Cancer

ISSN: 1471-2407

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