Skip to main content

Table 4 Final diagnosis

From: Relevance of blood tumor markers in inpatients with significant involuntary weight loss and elevated levels of inflammation biomarkers

  

TM-positive group

(N = 76)

TM-negative group

(N = 59)

 
 

Total

(N = 135)

Cancer

(N = 41)

No cancer

(N = 35)

Cancer

(N = 9)

No cancer

(N = 50)

p*

Cancer, n/N (%)

50/135 (37.0)

41/76 (53.9)

0/76

9/59 (15.3)

0/59

< 1.10-4

Organ, n/N (%)

      

Hematologic cancer

12/50 (24.0)

9/41 (22.0)

 

3/9 (33.3)

 

0.79

Upper digestive tract#

3/50 (6.0)

2/41 (4.9)

 

1/9 (11.1)

 

NA

Lower digestive tract§

5/50 (10.0)

3/41 (7.3)

 

2/9 (22.2)

 

NA

Liver

2 /50 (4.0)

2/41 (5.0)

 

0/9

 

NA

Pancreas

3/50 (6.0)

3/41 (7.3)

 

0/9

 

NA

Biliary tract

3/50 (6.0)

3/41 (7.3)

 

0/9

 

NA

Lung

7/50 (14.0)

6/41 (14.6)

 

1/9 (11.1)

 

NA

Breast

3/50 (6.0)

3/41 (7.3)

 

0/9

 

NA

Ovary

3/50 (6.0)

3/41 (7.3)

 

1/9 (11.1)

 

NA

Prostate

2/50 (4.0)

1/41 (2.4)

 

1/9 (11.1)

 

NA

Urinary tract

2/50 (4.0)

1/41 (2.4)

 

0/9

 

NA

Central nervous system

1/50 (2.0)

1/41 (2.4)

 

0/9

 

NA

Not known or uncertain

4 /50 (8.0)

4/41 (9.8)

 

0/9

 

NA

Histology, n/N(%)

      

Epithelial tumor

32/47 (68.1)

26/38(68.4)

 

6/9 (66.67)

 

1

Nonepithelial tumor

15/47(31.9)

12/38 (31.6)

 

3/9 (33.33)

 

1

- Neuroendocrine tumor

2/15 (12.5)

2/12 (16.7)

 

0/9

 

NA

- MPS

9/15 (56.3)

6/12 (50.0)

 

3/3 (100)

 

0.043

- LPS

1/15 (6.3)

1/12 (8.3)

 

0/3

 

NA

- MDS

2/15 (12.5)

2/12 (16.7)

 

0/3

 

NA

- GIST

1/15 (6.3)

1/12 (8.3)

 

0/3

 

NA

Stage, n/N(%)

      

I

5/42 (11.9)

3/33 (9.1)

 

2/9 (22.2)

 

NA

II

4/42 (9.5)

2/33 (6.1)

 

2/9 (22.2)

 

NA

III

2/42(4.8)

2/33 (6.1)

 

0/9

 

NA

IV

31/42 (73.8)

26/33 (78.8)

 

5/9 (55.6)

 

0.37

Benign disease, n/N(%)

81/135 (60.0)

 

35/76 (46.0)

 

46/59(78.0)

< 0.001

Infection

14/81 (17.3)

 

5/35 (14.3)

 

9/46 (19.6)

0.74

AID

45/81 (55.6)

 

22/35 (62.8)

 

23/46 (50)

0.35

Endocrinopathy

2/81(2.5)

 

1/35 (2.9)

 

1/46 (2.2)

NA

Digestive tract disorder

7/81 (8.6)

 

2/35 (5.7)

 

5/46 (10.9)

NA

Neurologic disorder

3/81 (3.7)

 

1/35 (2.9)

 

2/46 (4.3)

NA

Crystal arthropathy

2/81 (2.5)

 

2/35 (5.7)

 

0/46

NA

Adverse drug reactions

2/81(2.5)

 

0/35

 

2/46 (4.3)

NA

Other

6/81 (7.4)

 

2/35 (5.7)

 

4/46 (8.7)

NA

No final diagnosis, n/N(%)

4/135 (3.0)

 

0/35

 

4/50 (8.0)

NA

  1. Legends AID: autoimmune disease, GIST: gastrointestinal stromal tumor, LPS: lymphoproliferative syndrome, MDS: myelodysplasia syndrome, MPS: myeloproliferative syndrome, NA: not applicable
  2. * TM-positive patients vs. TM-negative patients