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Table 1 The patient clinical characteristics, baseline demographics and laboratory indictors

From: Phase I/II clinical trial of efficacy and safety of EGCG oxygen nebulization inhalation in the treatment of COVID-19 pneumonia patients with cancer

Factor

Patients (%)

 

Total n = 54

Gender

Male

44(81%)

Female

10(19%)

Age, median (range, years)

68 (37–78)

≥ 65

31(57%)

< 65

23(43%)

Histological subtype

Lung cancer

38(70%)

Esophageal cancer

13(24%)

Pleural mesothelioma

2(4%)

Breast cancer

1(2%)

Smoking history

Never smoke

28(52%)

Former/current smoker

26(48%)

ECOG performance status

0–1

23(43%)

≥ 2

31(57%)

AJCC stage

IA

1(2%)

IB

2(4%)

IIA

2(4%)

IIIA

7(13%)

IIIB

16(29%)

IIIC

6(11%)

IV

20(37%)

Combined with corticosteroid

Yes

11(20%)

No

43(80%)

Combined with antibiotic or antifungal drug

Yes

7(13%)

No

47(87%)

Oxygen saturation, %

95 (93–97)

Respiratory rate

23(17–29)

Respiratory support

No ventilator support*

26(48%)

Non-invasive ventilation

28(52%)

Laboratory parameters

White blood cell, x 10^9/L

5.9(3.4–9.6)

Lymphocyte, x 10^9/L

1.6(0.1–3.2)

IL-6, pg/mL

11.6(2.4–154)

Ferritin, ng/mL

305(11.2–1550)

C-reactive protein, mg/L

11.7(0.3-104.6)

Lactate dehydrogenase, u/L

241(144–1245)

  1. *include patients receiving low- or medium-flow nasal oxygen. ECOG PS, Eastern Cooperative Oncology Group Performance Status; AJCC stage, American Joint Committee on Cancer stage; IL-6, Interleukin-6