| RECIST 1.1 |  | mRECIST | ||||
---|---|---|---|---|---|---|---|
HAIC-LEN-PD1 | LEN-PD1 | P-value | Â | HAIC-LEN-PD1 | LEN-PD1 | P-value | |
Overall Reponse | n = 103 | n = 61 |  |  | n = 103 | n = 61 |  |
CR | 1 (0.9%) | 1 (1.6%) | Â | Â | 16 (15.5%) | 2 (3.3%) | Â |
PR | 65 (63.1%) | 8 (13.1%) | Â | Â | 63 (61.2%) | 12 (19.7%) | Â |
SD | 29 (28.2%) | 35 (57.4%) | Â | Â | 16 (15.5%) | 30 (49.1%) | Â |
PD | 8 (7.8%) | 17 (27.9%) | Â | Â | 8 (7.8%) | 17 (27.9%) | Â |
ORR | 66 (64.1%) | 9 (14.8%) | < 0.001 |  | 79 (76.7%) | 14 (23.0%) | < 0.001 |
DCR | 95 (92.2%) | 44 (72.1%) | 0.001 | Â | 95 (92.2%) | 44 (72.1%) | 0.001 |
Intrahepatic Response | n = 103 | n = 61 |  |  | n = 103 | n = 61 |  |
CR | 1 (0.9%) | 1 (1.6%) | Â | Â | 18 (17.5%) | 2 (3.3%) | Â |
PR | 67 (65.1%) | 9 (14.8%) | Â | Â | 65 (63.1%) | 13 (21.3%) | Â |
SD | 31 (30.1%) | 36 (59.0%) | Â | Â | 16 (15.5%) | 31 (50.8%) | Â |
PD | 4 (3.9%) | 15 (24.6%) | Â | Â | 4 (3.9%) | 15 (24.6%) | Â |
ORR | 68 (66.0%) | 10 (16.4%) | < 0.001 |  | 83 (80.6%) | 15 (24.6%) | < 0.001 |
DCR | 99 (96.1%) | 46 (75.4%) | < 0.001 |  | 99 (96.1%) | 46 (75.4%) | < 0.001 |