Table 2 Treatment characteristics
Treatment characteristics | ||||
|---|---|---|---|---|
Characteristic | Standard therapy (NT), n = 60 (%) | TNT, n = 17 (%) | Significance | |
Chemotherapy regimen | CAPEOX | 52 (86.6) | 12(70.5) | 0.043* |
m-FOLFOX6 | 08 (13.3) | 05(29.4) | ||
Surgery | Abdominoperineal Resection (APR) | 29 (13.3) | 11(64.7) | 0.70 |
Low Anterior Resection (LAR) | 31(51.6) | 06(35.2) | ||
Concurrent chemo radiotherapy (CCRT) | Yes | 60 (100) | 08(47) | 0.047* |
No | 00 | 09(53) | ||
Radiation Therapy (RT) | Short | 00 | 09(53) | 0.08 |
Long | 00 | 08(47) | ||
Histological grade | Well-differentiated | 47(78.00) | 07 (41.20) | 0.90 |
Moderately differentiated | 10(17.00) | 09 (53.00) | ||
Poorly differentiated | 03(5.00) | 01 (5.80) | ||
Circumferential Resection Margin (CRM) | Positive | 03 (05) | 01 (5.9) | 0.80 |
Negative | 43 (71.66) | 14 (82.4) | ||
Closed | 14 (23.33) | 02 (11.76) | ||
Perineural Invasion (PNI) | Present | 10 (16.66) | 03 (17.64) | 0.049* |
Absent | 50 (83.33) | 14 (82.35) | ||
Lymph Vascular Invasion (LVI) | Present | 8(13.33) | 02(11.76) | 0.047* |
Absent | 44(73.33) | 12 (70.58) | ||
Indeterminate | 8(13.33) | 03(17.76) | ||
T stage | T0 | 12 (20) | 09 (52.9) | 0.01* |
T1 | 06 (10) | 01 (5.8 | ||
T2 | 22 (36.6) | 02 (11.7) | ||
T3 | 17 (28.33) | 04 (23.5) | ||
T4 | 03 (05) | 01 (5.8) | ||
N stage | N0 | 25(41.66) | 12 (70.58) | 0.03* |
N1 | 20 (33.33) | 03 (05.00) | ||
N2 | 15 (25.00) | 02 (11.76) | ||
M stage | M0 | 52 (86.6) | 15 (88.2) | 0.01* |
M1 | 08 (13.3) | 02 (11.7) | ||