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Table 3 Univariate analysis of factors associated with PFS and OS

From: The prognostic role of pre-treatment neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in esophageal squamous cell carcinoma treated with concurrent chemoradiotherapy

Variable

PFS(months)

OS(months)

mPFS

95% CI

p

mOS

95% CI

p

NLR

  < 2.47

24.0

18.459–29.541

0.000

37

30.551–43.449

0.000

  ≥ 2.47

12.0

9.773–14.227

 

22

18.040–25.960

 

PLR

  < 136

24.0

20.145–27.835

0.000

35

30.268–39.732

0.000

  ≥ 136

12.0

10.597–13.403

 

24

20.708–27.292

 

Gender

 Male

18

15.163–20.837

0.111

29

25.720–32.280

0.089

 Female

19

14.151–23.849

 

31

25.839–36.161

 

Age (year)

  < 65

18

14.786–21.214

0.517

29

25.556–32.444

0.272

  ≥ 65

18

14.512–21.488

 

30

26.300–33.700

 

Smoking

 Yes

16

11.478–20.522

0.695

28

23.077–32.923

0.613

 No

19

16.718–21.282

 

31

28.015–33.985

 

Alcohol

 Yes

16

11.614–20.386

0.407

28

22.492–33.508

0.300

 No

19

16.720–21.280

 

30

27.149–32. 851

 

TNM Stage

 Stage I-II

25

18.574–31.426

0.000

37

28.095–45.905

0.000

 Stage III-IV

15

12.392–17.608

 

27

24.546–29.454

 

Tumor length

  < 5 cm

24

19.842–28.158

0.016

34

30.767–37.233

0.032

  ≥ 5 cm

15

12.321–17.679

 

27

24.382–29.618

 

Tumor location

 Upper thoracic

19

14.224–23.776

0.800

33

26.632–39.368

0.455

 Middle thoracic

16

10.668–21.332

 

30

25.397–34.603

 

 Lower thoracic

17

14.670–19.330

 

28

26.102–29. 898

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