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Fig. 2 | BMC Cancer

Fig. 2

From: Identification of BGN positive fibroblasts as a driving factor for colorectal cancer and development of its related prognostic model combined with machine learning

Fig. 2

Identification of BGN + Fibroblasts (BGN + Fib) as a relevant subgroup in CRC progression

A. Tsne plot of the nine fibroblast subgroups. B. Expression levels of the three fibroblast markers in the nine fibroblast subgroups. C. Heatmap of the top three markers for the nine fibroblast subgroups. D. GO/KEGG analysis of the nine fibroblast subgroups. E. tsne plot and proportion analysis of the normal and tumor groups. F. tsne plot and proportion analysis of different stages. G. Pseudo-time analysis. H. PPI network and hub gene identification of highly expressed genes (log2FC > 1, P < 0.05) in Fib_3. I. tsne plot and differential analysis of BGN expression. J. GSVA clustering heatmap

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