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Fig. 3 | BMC Cancer

Fig. 3

From: Identification of BGN positive fibroblasts as a driving factor for colorectal cancer and development of its related prognostic model combined with machine learning

Fig. 3

Increased expression of BGN + Fib in CRC and its association with poor prognosis and recurrence

A. The immunofluorescence results revealed the localization of BGN and the fibroblast-specific marker (α-SMA) in both normal fibroblasts (NF) and cancer-associated fibroblasts (CAFs). B. The immunofluorescence results of the tissue demonstrated the localization of BGN and α-SMA in both normal colon tissue and CRC tissue. C. Infiltration difference of BGN + Fib in normal and tumor tissues based on the TCGA-CRC cohort. D. Analysis of differences in BGN + Fib infiltration and CRC pathological features (T, N, M, and stage). E-F. Differences in OS/RFS between high and low BGN + Fib infiltration groups

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