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Table 2 Baseline characteristics between paclitaxel-sensitive and–resistant patients in the training set

From: Integrated clinical and genomic models using machine-learning methods to predict the efficacy of paclitaxel-based chemotherapy in patients with advanced gastric cancer

 

Paclitaxel-sensitive (N = 93, %)

Paclitaxel-resistant (N = 137, %)

P

Age (y)

   

Median, years (range)

64 (37–87)

64 (25–91)

0.910

< 40 years, n (%)

3 (3.2)

5 (3.6)

0.833

\( \ge \)70 years, n (%)

28 (30.1)

46 (33.6)

 

Sex

  

0.116

Male

57 (61.3)

98 (71.5)

 

Female

36 (28.5)

39 (28.5)

 

Histology

  

0.072

Intestinal type

51 (54.8)

92 (67.2)

 

Diffuse type

42 (45.2)

45 (32.8)

 

Clinical settings

  

0.132

Initially metastatic disease

57 (61.3)

97 (70.8)

 

Recurrent disease

36 (38.7)

40 (29.2)

 

Prior gastrectomy

56 (60.2)

64 (46.7)

0.059

Prior trastuzumab use

20 (21.5)

20 (14.6)

0.215

Duration of prior 1st -line fluoropyrimidine plus platinum– based chemotherapy

  

0.034

< 3 months

17 (18.3)

40 (29.2)

 

≥ 6 months

44 (47.3)

43 (31.4)

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