Table 3 Adjusted odds ratios for late versus early-stage CRC presentation, by region and sex

Age group in yrs

 0–39

0.95 (0.73, 1.17)

1.34 (1.14, 1.55)

0.95 (0.67, 1.23)

1.12 (0.84, 1.39)

 40–49

1.02 (0.83, 1.20)

1.32 (1.14, 1.50)

1.11 (0.88, 1.34)

1.05 (0.81, 1.29)

 50–59

1.00 P = 0.22

1.00 P < 0.01

1.00 P = 0.01

1.00 P = 0.02

 60–69

1.01 (0.84, 1.18)

1.09 (0.91, 1.27)

0.87 (0.66, 1.08)

1.10 (0.88, 1.33)

 70–79

1.11 (0.93, 1.28)

1.11 (0.90, 1.33)

1.10 (0.88, 1.32)

0.94 (0.69, 1.20)

 80+

1.13 (0.88, 1.37)

1.09 (0.80, 1.38)

1.23 (0.95, 1.52)

0.63 (0.26, 1.01)

Marital status

 Married

1.00 P = 0.85

1.00 P = 0.02

1.00 P = 0.30

1.00 P = 0.38

 Unmarried

1.07 (0.82, 1.31)

1.25 (1.09, 1.42)

1.23 (0.97, 1.49)

1.19 (0.99, 1.40)

Diagnosis date

 1997–2001

1.00 P < 0.0001

1.00 P = 0.02

1.00 P = 0.06

1.00 P < 0.0001

 2002–2006

1.16 (0.90, 1.42)

1.18 (0.91, 1.45)

1.40 (1.08, 1.71)

1.81 (1.44, 2.18)

 2007–2011

1.56 (1.32, 1.80)

1.39 (1.14, 1.64)

1.20 (0.90, 1.50)

1.85 (1.50, 2.19)

 2012–2017

1.34 (1.11, 1.57)

1.28 (1.05, 1.52)

1.13 (0.84, 1.42)

2.07 (1.73, 2.41)

Anatomical site

 Colon

1.00 P = 0.47

1.00 P < 0.01

1.00 P = 0.04

1.00 P = 0.92

 Rectosigmoid

1.09 (0.93, 1.25)

1.34 (1.16, 1.51)

1.29 (1.09, 1.49)

0.98 (0.76, 1.20)

 Rectal

0.99 (0.85, 1.12)

1.04 (0.89, 1.19)

0.98 (0.86, 1.15)

1.06 (0.86, 1.26)