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  2. Limited information is available for guiding the management of upper urinary tract (UUT) urothelial carcinoma with squamous differentiation (UC-SqD). We did not even know about the difference between pure uro...

    Authors: Li-Hua Huang, Chuan-Shu Chen, Jian-Ri Li, Kun-Yuan Chiu, Shian-Shiang Wang, Cheng-Kuang Yang, Chen-Li Cheng, Chi-Chien Lin and Yen-Chuan Ou
    Citation: BMC Cancer 2024 24:247
    Content type: Research Published on:

  3. Esophageal squamous cell carcinoma (ESCC) is a high-risk malignant tumor that has been reported in China. Some studies indicate that gut microbiota disorders can affect the occurrence and development of ESCC, ...

    Authors: Xingqiang Huang, Xueyi Chen, Guowei Wan, Dandan Yang, Dongqiang Zhu, Linqian Jia and Jinping Zheng
    Citation: BMC Cancer 2024 24:245
    Content type: Research Published on:

  4. Identifying risk factors for adverse pathologic features in low-risk papillary thyroid microcarcinoma (PTMC) can provide valuable insights into the necessity of surgical or non-surgical treatment. This study a...

    Authors: Lei Gong, Ping Li, Jingjing Liu, Yan Liu, Xinghong Guo, Weili Liang, Bin Lv, Peng Su and Kai Liang
    Citation: BMC Cancer 2024 24:244
    Content type: Research Published on:

  5. Women living with HIV are at risk for cervical dysplasia and cancer worldwide. In 2015, the World Health Organization (WHO) recommended that testing for high-risk HPV (hrHPV) infection be incorporated into cer...

    Authors: Harriet Nakigozi, Rawlance Ndejjo, William Bazeyo, Annet Nabaggala, Caroline Achola, Moses Iga, Simeon Kalyesubula, Ben Kanamwangi, Gerald Mutungi, Charles Batte, David Mukunya, Lawrence Sserwanga, Godfrey Gemageine, Charles Akiya Oyoo and Susan Nabadda
    Citation: BMC Cancer 2024 24:243
    Content type: Research Published on:

  6. To explore the association between preoperative WBC count and the long-term survival outcomes and clinical outcomes in different stage patients who underwent surgical resection for colorectal cancer (CRC).

    Authors: Bei Wang, Dandan Ling, Lihong Li, Jun Zhang and Jianghui Xu
    Citation: BMC Cancer 2024 24:242
    Content type: Research Published on:

  8. The benefit of adding Zolbetuximab to the treatment in patients with Claudin-18 isoform 2 (CLDN18.2)-positive, human epidermal growth factor receptor 2-negative, locally advanced unresectable or metastatic gas...

    Authors: Francisco Cezar Aquino de Moraes, Eric Pasqualotto, Matheus Pedrotti Chavez, Rafael Oliva Morgado Ferreira, Tiago Biachi De Castria and Rommel Mario Rodríguez Burbano
    Citation: BMC Cancer 2024 24:240
    Content type: Research Published on:

  11. Hepatocellular carcinoma (HCC) is a common malignant tumor with strong invasiveness and poor prognosis. Previous studies have demonstrated the significant role of USP14 in various solid tumors. However, the ro...

    Authors: Nannan Zhang, Hui Zhang, Xiaobing Yang, Qiang Xue, Quhui Wang, Renan Chang, Lirong Zhu, Zhong Chen and Xiancheng Liu
    Citation: BMC Cancer 2024 24:237
    Content type: Research Published on:

  14. Peroxisome proliferator-activated receptor gamma (PPARG) is a member of the nuclear receptor family. It is involved in the regulation of adipogenesis, lipid metabolism, insulin sensitivity, vascular homeostasi...

    Authors: Leah Schöckel, Christine Woischke, Sai Agash Surendran, Marlies Michl, Tobias Schiergens, Andreas Hölscher, Florian Glass, Peter Kreissl, Frederick Klauschen, Michael Günther, Steffen Ormanns and Jens Neumann
    Citation: BMC Cancer 2024 24:234
    Content type: Research Published on:

  15. Head and neck squamous cell carcinoma (HNSCC) constitutes one of the most common types of human cancers and often metastasizes to lymph nodes. Platinum-based chemotherapeutic drugs are commonly used for treatm...

    Authors: Abdulkader Yassin-Kassab, Suman Chatterjee, Nayel Khan, Nathaniel Wang, Vlad C. Sandulache, Eric H-B. Huang, Timothy F. Burns and Umamaheswar Duvvuri
    Citation: BMC Cancer 2024 24:233
    Content type: Research Published on:

  17. Minimally invasive distal pancreatectomy (MIDP), including laparoscopic and robotic distal pancreatectomy, has gained widespread acceptance over the last decade owing to its favorable short-term outcomes. Howe...

    Authors: Naoki Ikenaga, Tadayoshi Hashimoto, Junki Mizusawa, Ryo Kitabayashi, Yusuke Sano, Haruhiko Fukuda, Kohei Nakata, Kazuto Shibuya, Yuji Kitahata, Minoru Takada, Keiko Kamei, Hiroshi Kurahara, Daisuke Ban, Shogo Kobayashi, Hiroaki Nagano, Hajime Imamura…
    Citation: BMC Cancer 2024 24:231
    Content type: Study Protocol Published on:

  18. This study aimed to identify metabolic subtypes in ESCA, explore their relationship with immune landscapes, and establish a metabolic index for accurate prognosis assessment.

    Authors: Xiao-wan Yu, Pei-wei She, Fang-chuan Chen, Ya-yu Chen, Shuang Zhou, Xi-min Wang, Xiao-rong Lin, Qiao-ling Liu, Zhi-jun Huang and Yu Qiu
    Citation: BMC Cancer 2024 24:230
    Content type: Research Published on:

  20. The irreversible epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) afatinib and dacomitinib are approved for first-line treatment of EGFR mutation-positive non-small cell lung cancer (NSCLC)...

    Authors: Wen-Chien Cheng, Chi-Chien Lin, Wei-Chih Liao, Yu-Chao Lin, Chia-Hung Chen, Hung-Jen Chen, Chih-Yen Tu and Te-Chun Hsia
    Citation: BMC Cancer 2024 24:228
    Content type: Research Published on:

  21. Most patients with intrahepatic cholangiocarcinoma (ICC) have developed distant metastasis at the time of diagnosis, while there is rear related nomogram to predict the prognosis.

    Authors: Chen Yuan, Shubing Zou, Kai Wang and Zhigang Hu
    Citation: BMC Cancer 2024 24:227
    Content type: Research Published on:

  22. Systemic inflammatory factors can predict the survival prognosis of gastric cancer (GC) patients after neoadjuvant chemotherapy (NACT). However, whether longitudinal changes in systemic inflammatory factors ar...

    Authors: Hua-Long Zheng, Fu-Hai Wang, Ling-Kang Zhang, Ping Li, Chao-Hui Zheng, Qi-Yue Chen, Chang-Ming Huang and Jian-Wei Xie
    Citation: BMC Cancer 2024 24:226
    Content type: Research Published on:

  23. Hepatitis B virus (HBV) infections is an important public health problem worldwide and closely affect extrahepatic cancer. Several recent studies have investigated the relationship between HBV infection and he...

    Authors: Rukeng Tan, Xinyu Zhu, Yutong Sun, Shihao Yang, Chao Peng, Xinkai Feng, Zengyu Chen, Yiliyaer Yimamu, Guiqing Liao and Le Yang
    Citation: BMC Cancer 2024 24:225
    Content type: Research Published on:

  24. Breast ultrasound is highly sensitive, but its specificity is not as high for detecting malignant lesions. Auxiliary modalities like elastography, Color and Power Doppler ultrasound are used as adjuncts to yie...

    Authors: Mahboubeh Abedi, Leyla Sahebi, Bita Eslami, Azin Saberi, Marzieh Orouji, Sadaf Alipour and Shirin Shahsavarhaghighi
    Citation: BMC Cancer 2024 24:224
    Content type: Research Published on:

  25. The prognostic significance of the CRAFITY score (CRP and AFP in ImmunoTherapY) has been demonstrated in hepatocellular carcinoma (HCC) patients receiving immunotherapy. The purpose of this study was to investiga...

    Authors: Lijie Zhang, Tao Sun, Bo Sun, Kailu Zhang, Yuting Zheng, Na Li, Lei Chen, Chuansheng Zheng, Bin Liang and Heshui Shi
    Citation: BMC Cancer 2024 24:223
    Content type: Research Published on:

  26. Glioma is a primary brain tumor and the assessment of its molecular profile in a minimally invasive manner is important in determining treatment strategies. Among the molecular abnormalities of gliomas, mutati...

    Authors: Saiko Kino, Masayuki Kanamori, Yoshiteru Shimoda, Kuniyasu Niizuma, Hidenori Endo and Yuji Matsuura
    Citation: BMC Cancer 2024 24:222
    Content type: Research Published on:

  28. Glioblastoma (GBM) is a relatively prevalent primary tumor of the central nervous system in children, characterized by its high malignancy and mortality rates, along with the intricate challenges of achieving ...

    Authors: Gen Li, Liya Ma, Chenxi Feng, Hongli Yin, Jianping Bao, Di Wu, Zimu Zhang, Xiaolu Li, Zhiheng Li, Chun Yang, Hairong Wang, Fang Fang, Xiaohan Hu, Mei Li, Lixiao Xu, Yunyun Xu…
    Citation: BMC Cancer 2024 24:220
    Content type: Research Published on:

  29. Breast cancer is a common cause for central nervous system (CNS) metastasis, resulting in a significant reduction in overall survival. Germline pathogenic variants (PVs) in BRCA1/2 are the most common genetic ris...

    Authors: Matan Ben-Zion Berliner, Shlomit Yust-Katz, Inbar Lavie, Yael Goldberg, Inbal Kedar and Rinat Yerushalmi
    Citation: BMC Cancer 2024 24:219
    Content type: Research Published on:

  30. Bone metastases are frequently observed in advanced cancer, and bone modifying agents are used to prevent or treat skeletal-related events. Zoledronic acid is contraindicated in patients with severe renal impa...

    Authors: Kazuyo Nakamura, Michihiro Kaya, Yuki Yanagisawa, Keisuke Yamamoto, Nana Takayashiki, Hirotoshi Ukita, Mariko Nagura, Kaori Sugiue, Mariko Kitajima, Kumi Hirano, Hiroki Ishida, Chiharu Onoda, Yutaka Kobayashi, Eiji Nakatani, Keiichi Odagiri and Takaya Suzuki
    Citation: BMC Cancer 2024 24:218
    Content type: Research Published on:

  31. The aim of this study was to compare the therapeutic value and treatment-related complications of radical hysterectomy with those of concurrent chemoradiotherapy (CCRT) for locally resectable (T1a2–T2a1) stage...

    Authors: Mei-ling Zhong, Yin-chuan Liu, Jian-tong Yang, Ya-nan Wang, Mei-hong Ao, Yun Xiao, Si-yuan Zeng and Mei-rong Liang
    Citation: BMC Cancer 2024 24:217
    Content type: Research Published on:

  32. In the United States, the rate of benign histology among resected renal tumors suspected to be malignant is increasing. We evaluated the rates in the Republic of Korea and assessed the racial effect using rece...

    Authors: Chang Wook Jeong, Jang Hee Han, Seok Soo Byun, Cheryn Song, Sung-Hoo Hong, Jinsoo Chung, Seong Il Seo, Hong Koo Ha, Eu Chang Hwang, Ill Young Seo, Joseph G. Cheaib, Phillip M. Pierorazio, Misop Han and Cheol Kwak
    Citation: BMC Cancer 2024 24:216
    Content type: Research Published on:

  33. Genitourinary sarcomas are rare in adults and few large-scale studies on adult genitourinary sarcoma are reported. We aimed to elucidate the clinical characteristics, survival outcomes, and prognostic factors ...

    Authors: Satoshi Nitta, Shuya Kandori, Kosuke Kojo, Shuhei Suzuki, Kazuki Hamada, Ichiro Chihara, Masanobu Shiga, Shotaro Sakka, Yoshiyuki Nagumo, Tomokazu Kimura, Bryan J. Mathis, Hiromitsu Negoro, Ayako Okuyama, Takahiro Higashi and Hiroyuki Nishiyama
    Citation: BMC Cancer 2024 24:215
    Content type: Research Published on:

  34. Laryngeal squamous cell carcinoma (LSCC) is one of the most common types of cancer in the upper respiratory tract. It is well-known that it has a high mortality rate and poor prognosis in advanced stages. Ther...

    Authors: Tomas Jakstas, Agne Bartnykaite, Evaldas Padervinskis, Aurelija Vegiene, Elona Juozaityte, Virgilijus Uloza and Rasa Ugenskiene
    Citation: BMC Cancer 2024 24:214
    Content type: Research Published on:

  35. The clinical significance of single cell invasion and large nuclear diameter is not well documented in early-stage oral tongue squamous cell carcinoma (OTSCC).

    Authors: Alhadi Almangush, Jaana Hagström, Caj Haglund, Luiz Paulo Kowalski, Ricardo D. Coletta, Antti A. Mäkitie, Tuula Salo and Ilmo Leivo
    Citation: BMC Cancer 2024 24:213
    Content type: Research Published on:

  36. To screen the risk factors affecting the recurrence risk of patients with ampullary carcinoma (AC)after radical resection, and then to construct a model for risk prediction based on Lasso-Cox regression and vi...

    Authors: Ruiqiu Chen, Lin Zhu, Yibin Zhang, Dongyu Cui, Ruixiang Chen, Hao Guo, Li Peng and Chaohui Xiao
    Citation: BMC Cancer 2024 24:212
    Content type: Research Published on:

  37. Lung cancer significantly impairs exercise capacity and health-related quality of life (HRQL). Pulmonary rehabilitation (PR) has demonstrated positive effects on exercise capacity and HRQL in lung cancer patie...

    Authors: Chun-Yao Huang, Min-Shiau Hsieh, Po-Chun Hsieh, Yao-Kuang Wu, Mei-Chen Yang, Shiang-Yu Huang, I-Shiang Tzeng and Chou-Chin Lan
    Citation: BMC Cancer 2024 24:211
    Content type: Research Published on:

  39. Cancer-associated fibroblasts (CAFs) play an important role in the tumor microenvironment. Despite the well-known in vitro antitumoral effect of vitamin D3 (VD3), its impact on breast CAFs is almost unknown. In t...

    Authors: Natalia Łabędź, Artur Anisiewicz, Martyna Stachowicz-Suhs, Joanna Banach, Dagmara Kłopotowska, Adam Maciejczyk, Patrycja Gazińska, Aleksandra Piotrowska, Piotr Dzięgiel, Rafał Matkowski and Joanna Wietrzyk
    Citation: BMC Cancer 2024 24:209
    Content type: Research Published on:

  40. Despite the known association between healthy lifestyles and reduced risk of breast cancer, it remains unclear whether systemic inflammation, as a consequence of unhealthy lifestyles, may mediate the association.

    Authors: Yanyu Zhang, Mengjie Song, Zixuan Yang, Xiaoxi Huang, Yuxiang Lin and Haomin Yang
    Citation: BMC Cancer 2024 24:208
    Content type: Research Published on:

  41. Ovarian cancer (OC) is a complex disease with significant tumor heterogeneity with the worst prognosis and highest mortality among all gynecological cancers. Glycosylation is a specific post-translational modi...

    Authors: Yue You and Qing Yang
    Citation: BMC Cancer 2024 24:207
    Content type: Research Published on:

  42. This study is designed to explore the potential impact of individual and environmental residential factors as risk determinants for bone and soft tissue cancers, with a particular focus on the Indonesian conte...

    Authors: Yusuf Alam Romadhon, Yuni Prastyo Kurniati, Jumadi Jumadi, Ali Asghar Alesheikh and Aynaz Lotfata
    Citation: BMC Cancer 2024 24:206
    Content type: Research Published on:

  44. Colorectal cancer (CRC) is an aggressive tumor of the gastrointestinal tract, which is a major public health concern worldwide. Despite numerous studies, the precise mechanism of metastasis behind its progress...

    Authors: Yong Tang, Yi Liu, Xiaobo Wang, Haiyang Guo, Lin Chen, Guangbing Hu, Yutong Cui, Shiqi Liang, Ji Zuo, Zichen Luo, Xinrui Chen and Xianfei Wang
    Citation: BMC Cancer 2024 24:204
    Content type: Research Published on:

  45. Chemotherapy is included in treatment regimens for many solid cancers, but when administered as a single agent it is rarely curative. The addition of immune checkpoint therapy to standard chemotherapy regimens...

    Authors: Caitlin M. Tilsed, M. Lizeth Orozco Morales, Rachael M. Zemek, Brianna A. Gordon, Matthew J. Piggott, Anna K. Nowak, Scott A. Fisher, Richard A. Lake and W. Joost Lesterhuis
    Citation: BMC Cancer 2024 24:203
    Content type: Research Published on:

  46. A combination of immune checkpoint inhibitors (ICIs) and chemotherapy has demonstrated excellent clinical efficacy and safety in treating a variety of cancers, including urothelial carcinoma (UC). However, its...

    Authors: Jingwen Zhang, Meng Yang, Dongqun Wei, Deru Zhang, Zeyu Chen and Haitao Zhu
    Citation: BMC Cancer 2024 24:202
    Content type: Research Published on:

  47. For patients with liver-confined metastatic colorectal cancer (mCRC), local therapy of isolated metastases has been associated with long-term progression-free and overall survival (OS). However, for patients w...

    Authors: Kathryn E. Hitchcock, Eric D. Miller, Qian Shi, Jesse G. Dixon, Sepideh Gholami, Sarah B. White, Christina Wu, Christopher C. Goulet, Manju George, Kyung-Wook Jee, Chadwick L. Wright, Rona Yaeger, Ardaman Shergill, Theodore S. Hong, Thomas J. George, Eileen M. O’Reilly…
    Citation: BMC Cancer 2024 24:201
    Content type: Study Protocol Published on:

  48. EGFR inhibitor and immunotherapy have been approved for adjuvant treatment in resectable non-small cell lung cancer (NSCLC). Limited reports of molecular and clinical characteristics as prognostic factors in N...

    Authors: T. Thamrongjirapat, D. Muntham, P. Incharoen, N. Trachu, P. Sae-Lim, N. Sarachai, K. Khiewngam, N. Monnamo, N. Kantathut, M. Ngodngamthaweesuk, T. Ativitavas, P. Chansriwong, C. Nitiwarangkul, R. Ruangkanchanasetr, A. Kositwattanarerk, E. Sirachainan…
    Citation: BMC Cancer 2024 24:200
    Content type: Research Published on:

  49. Glioblastoma (GBM) is an aggressive brain tumor that exhibits resistance to current treatment, making the identification of novel therapeutic targets essential. In this context, cellular prion protein (PrPC) stan...

    Authors: Jacqueline Marcia Boccacino, Rafael dos Santos Peixoto, Camila Felix de Lima Fernandes, Giovanni Cangiano, Paula Rodrigues Sola, Bárbara Paranhos Coelho, Mariana Brandão Prado, Maria Isabel Melo-Escobar, Breno Pereira de Sousa, Shamini Ayyadhury, Gary D. Bader, Sueli Mieko Oba Shinjo, Suely Kazue Nagahashi Marie, Edroaldo Lummertz da Rocha and Marilene Hohmuth Lopes
    Citation: BMC Cancer 2024 24:199
    Content type: Research Published on:

  50. In the management of urothelial carcinoma, patient selection for immunotherapy, particularly with immune checkpoint inhibitors such as PD-1 (programmed cell death protein 1), is important for treatment effica...

    Authors: Meng Yang, Jingwen Zhang, Dongqun Wei, Tianyi Yu, Zeyu Chen, Xin Liu and Haitao Zhu
    Citation: BMC Cancer 2024 24:196
    Content type: Research Published on:

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