Table 1 Patient and tumor characteristics (n = 108)

Age (years)

 Mean ± standard deviation

58.4 ± 10.2

 Median (range)

59 (29–78)

ECOG performance status on chemotherapy day 1

 0

42

39

 1

57

53

 2

8

7

HER2 overexpression

2+/FISH +

8

7

3+

97

90

FISH +/no immunohistochemistry or other

3

3

Tumor grade (n = 102)

 G1

2

2

 G2

47

46

 G3

53

52

Metastatic sites at onset of study treatment (n)

 Mean ± standard deviation

1.8 ± 0.9

 Median, range

2 (1–5)

Organ site involvement

 Local/skin

14

13

 Lymph nodes, non-regional

20

19

 Bone

41

38

 Liver

48

44

 Lung

49

45

 Pleural effusion

13

12

 Genitourinary

1

1

 Other

9

8

Previous treatment

 Neoadjuvant chemotherapy

11

10

 Adjuvant chemotherapy

74

69

 Adjuvant endocrine therapy

45

42

 Palliative chemotherapy

40

37

 Palliative endocrine therapy

34

31